{"id":1033,"date":"2017-02-09T18:22:14","date_gmt":"2017-02-09T18:22:14","guid":{"rendered":"http:\/\/hfhpulm.com\/info\/?p=1033"},"modified":"2017-03-09T13:52:16","modified_gmt":"2017-03-09T13:52:16","slug":"noteworthy-recent-articles-copd","status":"publish","type":"post","link":"https:\/\/hfhpulm.com\/info\/?p=1033","title":{"rendered":"Noteworthy recent articles for COPD"},"content":{"rendered":"

Not all-inclusive and can be updated. These are recent articles with findings that may impact or change how you currently practice.<\/p>\n

1. Noninvasive ventilation in patients with chronic hypercapnea improves survival, if the PCO2 was lowered by 20% (or to 48 mmHg).
\nLancet 2014<\/a><\/p>\n

2. NAC for exacerbations. Meta-analysis Eur Respir Rev 2015; 24: 451\u2013461<\/a>. In patients with chronic bronchitis, N-acetylcysteine decreases the rate of exacerbations. The data shows that if the patient has an airway obstruction, NAC should be administered at a dose of
\n\u2a7e1200 mg per day to prevent exacerbations, while if a patient suffers from chronic bronchitis, but is
\nwithout airway obstruction, a regular treatment of 600 mg per day seems to be sufficient.<\/p>\n

3. LOTT study (NEJM 375:1617 2016 )
\nIn patients with stable COPD and resting desaturation (89 to 93%) or exercise-induced moderate desaturation, long-term supplemental oxygen did not<\/strong> result in a longer time to death or first hospitalization than no long-term supplemental oxygen, nor did it provide sustained
\nbenefit with regard to any of the other measured outcomes.<\/p>\n","protected":false},"excerpt":{"rendered":"

Not all-inclusive and can be updated. These are recent articles with findings that may impact or change how you currently practice. 1. Noninvasive ventilation in patients with chronic hypercapnea improves survival, if the PCO2 was lowered by 20% (or to 48 mmHg). Lancet 2014 2. NAC for exacerbations. Meta-analysis Eur Respir Rev 2015; 24: 451–461. […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[96,21],"tags":[],"class_list":["post-1033","post","type-post","status-publish","format-standard","hentry","category-curriculum","category-virtual-journal-club"],"modified_by":"Jennings","_links":{"self":[{"href":"https:\/\/hfhpulm.com\/info\/index.php?rest_route=\/wp\/v2\/posts\/1033","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hfhpulm.com\/info\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hfhpulm.com\/info\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hfhpulm.com\/info\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/hfhpulm.com\/info\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1033"}],"version-history":[{"count":7,"href":"https:\/\/hfhpulm.com\/info\/index.php?rest_route=\/wp\/v2\/posts\/1033\/revisions"}],"predecessor-version":[{"id":1050,"href":"https:\/\/hfhpulm.com\/info\/index.php?rest_route=\/wp\/v2\/posts\/1033\/revisions\/1050"}],"wp:attachment":[{"href":"https:\/\/hfhpulm.com\/info\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1033"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hfhpulm.com\/info\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1033"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hfhpulm.com\/info\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1033"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}