Pneumococcal Vaccination (Prevnar 20)

(Originally posted on: December 29, 2022

Prevnar 20 is now stocked at Henry Ford Main Campus on K17 and throughout this year it will be available at the satellite clinics. It will take the place of both Prevnar 13 and 23.

The epic order is IMM216

Patients >65 if received both Prevnar 13 and Prevnar 23 after age 65 would not need vaccination.

Patients 19-64 if received both Prevnar 13 and Prevnar 23 would not require Prevnar 20 until age 65.

Below are further recommendations by CDC

Patients 19-64

Underlying ConditionPrevious vaccinePneumococcal vaccine recommended
NoneNoneNo pneumococcal vaccine indicated
Chronic medical conditions with increased risk of pneumococcal disease1
Cerebrospinal Fluid Leak or cochlear implant or immunocompromising conditions 2
None1 dose of PCV20
Chronic medical conditions with increased risk of pneumococcal disease1
Cerebrospinal Fluid Leak or cochlear implant or immunocompromising conditions 2
PPSV23 given1 dose of PCV20, 1 year after the PPSV23
Chronic medical conditions with increased risk of pneumococcal disease1PCV13 given1 dose of PCV20, 1 year after the PCV13
Chronic medical conditions with increased risk of pneumococcal disease1PCV13 given and 1 dose PPSV23 givenNo additional doses when younger than age 65 years
Chronic medical conditions with increased risk of pneumococcal disease1PCV13 given and 2 doses PPSV23 givenNo additional doses when younger than age 65 years
Cerebrospinal Fluid Leak or cochlear implant or immunocompromising conditions 2PCV13 given1 dose of PCV20, 8 weeks after the PCV13
Cerebrospinal Fluid Leak or cochlear implantPCV13 given and 1 dose PPSV23 givenNo additional dose when less than 65 years of age
Immunocompromising conditions 2PCV13 given and 1 dose PPSV23 given1 dose of PCV20 5 years after PPSV23
Immunocompromising conditions 2PCV13 given and 2 dose of PPSV23No additional dose when less than 65 years of age

Patients 65 and Older

Underlying ConditionPrevious vaccinePneumococcal vaccine recommended
All patients 65 years of age and olderNone1 dose of PCV20
All patients 65 years of age and olderPPSV23 given1 dose of PCV20, 1 year after the PPSV23
All patients 65 years of age and olderPCV13 given and PPSV23 given after the age of 65No additional vaccine recommended
None
OR
Chronic medical conditions with increased risk of pneumococcal disease1
PCV13 given1 dose of PCV20, 1 year after the PCV13
None
OR
Chronic medical conditions with increased risk of pneumococcal disease1
PCV13 given and PPSV23 given before the age of 651 dose of PCV20, 1 year after the PCV13
Cerebrospinal Fluid Leak or cochlear implant or immunocompromising conditions 2PCV13 given1 dose of PCV20, 8 weeks after the PCV13
Cerebrospinal Fluid Leak or cochlear implant or immunocompromising conditions 2PCV13 given and PPSV23 given before the age of 651 dose of PCV20, 8 weeks after the PCV13

1 Chronic medical conditions with increased risk of pneumococcal disease- Alcoholism, Chronic heart disease (includes CHF and cardiomyopathies); Chronic liver disease; Chronic lung disease (includes COPD, emphysema, and asthma); Cigarette smoking; Diabetes mellitus

2 immunocompromising conditions – Sickle cell disease/ other hemoglobinopathies, Congenital/acquired asplenia, HIV, Chronic renal failure, Nephrotic syndrome, Leukemia, Lymphoma, Hodgkin Disease, Generalized malignancy, Multiple myeloma, Congenital or acquired Immunodeficiencies (includes B-(Humoral) or T- lymphocyte deficiency, complement deficiencies (particularly C1, C2 , C3, and C4 deficiencies) and phagocytic disorders (excluding chronic granulomatous disease), Iatrogenic immunosuppression (diseases requiring treatment with immunosuppressive drugs, including long-term corticosteroids, and radiation therapy); solid organ transplant.

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