Premedication for contrast allergy

(Originally posted on: April 10, 2015

Routine/Elective

Prednisone 50 mg PO Q6H x 3 doses
Administer 13 hours, 7 hours, and 1 hour before contrast media
Diphenhydramine (Benadryl) 50 mg PO x 1 dose
Administer 1 hour before contrast media

Routine/Elective and patient unable to tolerate oral medications

Methylprednisolone (Solu-Medrol) 40 mg IV Q6H x 3 doses
Administer 13 hours, 7 hours, and 1 hour before contrast media
Diphenhydramine (Benadryl) 50 mg IV/IM x 1 dose
Administer 1 hour before contrast media

Urgent

Methylprednisolone (Solu-Medrol) 40 mg IV Q4H
Administer every 4 hours until contrast media*
Diphenhydramine (Benadryl) 50 mg IV x 1 dose
Administer 1 hour before contrast media

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