TIME TO RESTART MEDICATIONS AFTER BRONCHOSCOPY WITH BIOPSIES
Heparin SubQ
No Need to stop
Not applicable
Enoxaparin 1mg/Kg SubQ BID
> 24 hours
> 12 hours
Enoxaparin 1.5mg/Kg SubQ QD
> 24 hours
> 12 hours
Warfarin (Coumadin)
5 days (confirm INR < 1.5)
immediately
Heparin IV
> 4 hours (check PTT)
> 4 hours (no bolus)
Fondaparinux (Arixtra)
> 48 hours
> 12 hours
Rivaroxaban (Xarelto)
> 36 hours
> 24 hours
Apixaban (Eliquis)
3 days
> 12 hours
Streptokinase (Local)
No Need to stop
Alteplase (Local)
No Need to stop
Alteplase (Systemic)
10 days
10 days
Streptokinase (Systemic)
10 days
10 days
Urokinase (Systemic)
10 days
10 days
Aspirin
No Need to stop
NSAID
No Need to stop
ASA/Dipyridamole (Aggrenox)
> 24 hours
immediately
Abciximab (Reopro)
> 48 hours (check platelet/PTT)
> 4 hours
Cilostazol (Pletal)
5 days
> 6 hours
Clopidogrel (Plavix)
7 days
immediately
Eptifibatide (Integrilin)
8 hours (check Platelet/PTT)
> 4 hours
Tirofiban (Aggrastat)
8 hours (check Platelet/PTT)
> 4 hours
Ticagrelor (Brilinta)
> 7 days
> 6 hours
Ticlopidine (Ticlid)
14 days
immediately
Prasugrel (Effient)
10 days
> 8 hours
Argatroban (Acova)
> 4 hours (check PTT)
> 2 hours
Dagitraban (Pradaxa)
7 days
> 6 hours
Bevalirudin (Angiomax)
> 10 hours
> 4 hours
Desirudin (Revasc)
> 10 hours
> 4 hours
Lepirudin (Refludan)
> 10 hours
> 4 hours
Time to resume anticoagulants COULD BE CHANGED by physician
References:
Regional Anesthesia and Antithrombotic Agents.: Recommendations of the European Society of Anesthesiology. European Journal of Anaesthesiology 2010; 27: 999-1015
