A prospective trial published in 2012 compared a chloride-restricted fluid strategy with a chloride-liberal strategy for critically ill patients. What were the findings of this study?
JAMA 2012;308(15):1566-1572
There was an additional study published in 2015 evaluating hyperchloremia in critically ill septic patients. What were the findings of this study?
Crit Care Med 2015 Sep;43(9):1938-44
Based on these two studies, what do you conclude? How do you approach fluid management with respect to chloride?